Somatic diversification in the absence of antigen-driven responses is the hallmark of the IgM(+)IgD(+)CD27(+) B cell repertoire in infants

T cell–dependent immune responses develop soon after birth, whereas it takes 2 yr for humans to develop T cell–independent responses. We used this dissociation to analyze the repertoire diversification of IgM(+)IgD(+)CD27(+) B cells (also known as “IgM memory” B cells), comparing these cells with sw...

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Detalles Bibliográficos
Autores principales: Weller, Sandra, Mamani-Matsuda, Maria, Picard, Capucine, Cordier, Corinne, Lecoeuche, Damiana, Gauthier, Frédéric, Weill, Jean-Claude, Reynaud, Claude-Agnès
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413031/
https://www.ncbi.nlm.nih.gov/pubmed/18519648
http://dx.doi.org/10.1084/jem.20071555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413031/
https://www.ncbi.nlm.nih.gov/pubmed/18519648
http://dx.doi.org/10.1084/jem.20071555

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