Membrane traffic and turnover in TRP-ML1–deficient cells: a revised model for mucolipidosis type IV pathogenesis

The lysosomal storage disorder mucolipidosis type IV (MLIV) is caused by mutations in the transient receptor potential–mucolipin-1 (TRP-ML1) ion channel. The “biogenesis” model for MLIV pathogenesis suggests that TRP-ML1 modulates postendocytic delivery to lysosomes by regulating interactions betwee...

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Detalles Bibliográficos
Autores principales: Miedel, Mark T., Rbaibi, Youssef, Guerriero, Christopher J., Colletti, Grace, Weixel, Kelly M., Weisz, Ora A., Kiselyov, Kirill
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413042/
https://www.ncbi.nlm.nih.gov/pubmed/18504305
http://dx.doi.org/10.1084/jem.20072194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413042/
https://www.ncbi.nlm.nih.gov/pubmed/18504305
http://dx.doi.org/10.1084/jem.20072194

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