Silencing α-Synuclein Gene Expression Enhances Tyrosine Hydroxylase Activity in MN9D Cells

α-Synuclein has been implicated in the pathogenesis of Parkinson’s disease (PD). Previous studies have shown that α-synuclein is involved in the regulation of dopamine (DA) metabolism, possibly by down-regulating the expression of tyrosine hydroxylase (TH), the rate-limiting enzyme in DA biosynthesi...

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Detalles Bibliográficos
Autores principales: Liu, Dongmei, Jin, Ling, Wang, Hao, Zhao, Huanying, Zhao, Chunli, Duan, Chunli, Lu, Lingling, Wu, Bo, Yu, Shun, Chan, Piu, Li, Yaohua, Yang, Hui
Formato: Texto
Lenguaje:English
Publicado: Springer US 2008
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413118/
https://www.ncbi.nlm.nih.gov/pubmed/18357527
http://dx.doi.org/10.1007/s11064-008-9599-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413118/
https://www.ncbi.nlm.nih.gov/pubmed/18357527
http://dx.doi.org/10.1007/s11064-008-9599-7

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