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Carbenoxolone induced depression of rhythmogenesis in the pre-Bötzinger Complex

BACKGROUND: Carbenoxolone (CBX), a gap junction uncoupler, alters the functioning of the pre-Bötzinger Complex (preBötC), a central pattern generating neuronal network important for the production of respiratory rhythm in mammals. Even when isolated in a 1/2 mm-thick slice of medulla oblongata from...

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Detalles Bibliográficos
Autores principales: Elsen, Frank P, Shields, Edward J, Roe, Matthew T, VanDam, Richard J, Kelty, Jonathan D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413244/
https://www.ncbi.nlm.nih.gov/pubmed/18500991
http://dx.doi.org/10.1186/1471-2202-9-46