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Cytosolic Sequestration of Prep1 Influences Early Stages of T Cell Development
OBJECTIVE: Prep1 and Pbx2 are the main homeodomain DNA-binding proteins of the TALE (three amino acid loop extension) family expressed in the thymus. We previously reported reduced Pbx2 expression and defective thymocyte maturation in Prep1 hypomorphic mice. To further investigate the role of this h...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413408/ https://www.ncbi.nlm.nih.gov/pubmed/18560600 http://dx.doi.org/10.1371/journal.pone.0002424 |