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Exosomes Derived from M. Bovis BCG Infected Macrophages Activate Antigen-Specific CD4(+) and CD8(+) T Cells In Vitro and In Vivo
Activation of both CD4(+) and CD8(+) T cells is required for an effective immune response to an M. tuberculosis infection. However, infected macrophages are poor antigen presenting cells and may be spatially separated from recruited T cells, thus limiting antigen presentation within a granuloma. Our...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413420/ https://www.ncbi.nlm.nih.gov/pubmed/18560543 http://dx.doi.org/10.1371/journal.pone.0002461 |