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Free Brick1 Is a Trimeric Precursor in the Assembly of a Functional Wave Complex

BACKGROUND: The Wave complex activates the Arp2/3 complex, inducing actin polymerization in lamellipodia and membrane ruffles. The Wave complex is composed of five subunits, the smallest of which, Brick1/Hspc300 (Brk1), is the least characterized. We previously reported that, unlike the other subuni...

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Detalles Bibliográficos
Autores principales: Derivery, Emmanuel, Fink, Jenny, Martin, Davy, Houdusse, Anne, Piel, Matthieu, Stradal, Theresia E., Louvard, Daniel, Gautreau, Alexis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413427/
https://www.ncbi.nlm.nih.gov/pubmed/18560548
http://dx.doi.org/10.1371/journal.pone.0002462