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Adaptive design methods in clinical trials – a review
In recent years, the use of adaptive design methods in clinical research and development based on accrued data has become very popular due to its flexibility and efficiency. Based on adaptations applied, adaptive designs can be classified into three categories: prospective, concurrent (ad hoc), and...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2422839/ https://www.ncbi.nlm.nih.gov/pubmed/18454853 http://dx.doi.org/10.1186/1750-1172-3-11 |