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The Mechanisms of Catalysis by Metallo β-Lactamases

Class B β-lactamases or metallo-β-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of β-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins. There are no clinically useful inhibitors against MBLs which are responsible for the resistance of some bacteria...

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Detalles Bibliográficos
Autores principales: Page, Michael I., Badarau, Adriana
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2422870/
https://www.ncbi.nlm.nih.gov/pubmed/18551183
http://dx.doi.org/10.1155/2008/576297