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The look-ahead effect of phenotypic mutations

BACKGROUND: The evolution of complex molecular traits such as disulphide bridges often requires multiple mutations. The intermediate steps in such evolutionary trajectories are likely to be selectively neutral or deleterious. Therefore, large populations and long times may be required to evolve such...

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Detalles Bibliográficos
Autores principales: Whitehead, Dion J, Wilke, Claus O, Vernazobres, David, Bornberg-Bauer, Erich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423361/
https://www.ncbi.nlm.nih.gov/pubmed/18479505
http://dx.doi.org/10.1186/1745-6150-3-18