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The look-ahead effect of phenotypic mutations
BACKGROUND: The evolution of complex molecular traits such as disulphide bridges often requires multiple mutations. The intermediate steps in such evolutionary trajectories are likely to be selectively neutral or deleterious. Therefore, large populations and long times may be required to evolve such...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423361/ https://www.ncbi.nlm.nih.gov/pubmed/18479505 http://dx.doi.org/10.1186/1745-6150-3-18 |