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Low-level expression of HER2 and CK19 in normal peripheral blood mononuclear cells: relevance for detection of circulating tumor cells

BACKGROUND: Detection of circulating tumor cells (CTC) in the blood of cancer patients may have prognostic and predictive significance. However, background expression of 'tumor specific markers' in peripheral blood mononuclear cells (PBMC) may confound these studies. The goal of this study...

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Detalles Bibliográficos
Autores principales: You, Fanglei, Roberts, Lisa A, Kang, S Peter, Nunes, Raquel A, Dias, Cinara, Iglehart, J Dirk, Solomon, Natalie A, Friedman, Paula N, Harris, Lyndsay N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423476/
https://www.ncbi.nlm.nih.gov/pubmed/18577250
http://dx.doi.org/10.1186/1756-8722-1-2