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Dynamics of Immune Escape during HIV/SIV Infection

Several studies have shown that cytotoxic T lymphocytes (CTLs) play an important role in controlling HIV/SIV infection. Notably, the observation of escape mutants suggests a selective pressure induced by the CTL response. However, it remains difficult to assess the definite role of the cellular immu...

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Detalles Bibliográficos
Autores principales: Althaus, Christian L., De Boer, Rob J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423483/
https://www.ncbi.nlm.nih.gov/pubmed/18636096
http://dx.doi.org/10.1371/journal.pcbi.1000103