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Dopamine Agonist Increases Risk Taking but Blunts Reward-Related Brain Activity

The use of D2/D3 dopaminergic agonists in Parkinson's disease (PD) may lead to pathological gambling. In a placebo-controlled double-blind study in healthy volunteers, we observed riskier choices in a lottery task after administration of the D3 receptor-preferring agonist pramipexole thus mimic...

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Detalles Bibliográficos
Autores principales: Riba, Jordi, Krämer, Ulrike M., Heldmann, Marcus, Richter, Sylvia, Münte, Thomas F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423613/
https://www.ncbi.nlm.nih.gov/pubmed/18575579
http://dx.doi.org/10.1371/journal.pone.0002479