Hepatotoxin-Induced Changes in the Adult Murine Liver Promote MYC-Induced Tumorigenesis

BACKGROUND: Overexpression of the human c-MYC (MYC) oncogene is one of the most frequently implicated events in the pathogenesis of hepatocellular carcinoma (HCC). Previously, we have shown in a conditional transgenic mouse model that MYC overexpression is restrained from inducing mitotic cellular d...

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Detalles Bibliográficos
Autores principales: Beer, Shelly, Komatsubara, Kimberly, Bellovin, David I., Kurobe, Masashi, Sylvester, Karl, Felsher, Dean W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423614/
https://www.ncbi.nlm.nih.gov/pubmed/18560566
http://dx.doi.org/10.1371/journal.pone.0002493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423614/
https://www.ncbi.nlm.nih.gov/pubmed/18560566
http://dx.doi.org/10.1371/journal.pone.0002493

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