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Hepatotoxin-Induced Changes in the Adult Murine Liver Promote MYC-Induced Tumorigenesis

BACKGROUND: Overexpression of the human c-MYC (MYC) oncogene is one of the most frequently implicated events in the pathogenesis of hepatocellular carcinoma (HCC). Previously, we have shown in a conditional transgenic mouse model that MYC overexpression is restrained from inducing mitotic cellular d...

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Detalles Bibliográficos
Autores principales:	Beer, Shelly, Komatsubara, Kimberly, Bellovin, David I., Kurobe, Masashi, Sylvester, Karl, Felsher, Dean W.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423614/ https://www.ncbi.nlm.nih.gov/pubmed/18560566 http://dx.doi.org/10.1371/journal.pone.0002493

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