B-MYB Is Essential for Normal Cell Cycle Progression and Chromosomal Stability of Embryonic Stem Cells

BACKGROUND: The transcription factor B-Myb is present in all proliferating cells, and in mice engineered to remove this gene, embryos die in utero just after implantation due to inner cell mass defects. This lethal phenotype has generally been attributed to a proliferation defect in the cell cycle p...

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Detalles Bibliográficos
Autores principales: Tarasov, Kirill V., Tarasova, Yelena S., Tam, Wai Leong, Riordon, Daniel R., Elliott, Steven T., Kania, Gabriela, Li, Jinliang, Yamanaka, Satoshi, Crider, David G., Testa, Gianluca, Li, Ronald A., Lim, Bing, Stewart, Colin L., Liu, Yie, Van Eyk, Jennifer E., Wersto, Robert P., Wobus, Anna M., Boheler, Kenneth R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423619/
https://www.ncbi.nlm.nih.gov/pubmed/18575582
http://dx.doi.org/10.1371/journal.pone.0002478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423619/
https://www.ncbi.nlm.nih.gov/pubmed/18575582
http://dx.doi.org/10.1371/journal.pone.0002478

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