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Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor-bearing mice

BACKGROUND: Interleukin-12 (IL-12) is a cytokine well known for its role in immunity. A lesser known function of IL-12 is its role in hematopoiesis. The promising data obtained in the preclinical models of antitumor immunotherapy raised hope that IL-12 could be a powerful therapeutic agent against c...

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Detalles Bibliográficos
Autores principales: Basile, Lena A, Gallaher, Timothy K, Shibata, Darryl, Miller, Joseph D, Douer, Dan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424034/
https://www.ncbi.nlm.nih.gov/pubmed/18489769
http://dx.doi.org/10.1186/1479-5876-6-26