Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules

OBJECTIVE: Here we report the improved results of a new siRNA design program and analysis tool called siRNA_profile that reveals an additional criterion for bioinformatic search of highly functional siRNA sequences. METHODS: We retrospectively analysed over 2400 siRNA sequences from 34 genes and wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Muhonen, Pirkko, Parthasarathy, Ranga N, Janckila, Anthony J, Büki, Kalman G, Väänänen, H Kalervo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424050/
https://www.ncbi.nlm.nih.gov/pubmed/18495017
http://dx.doi.org/10.1186/1751-0473-3-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424050/
https://www.ncbi.nlm.nih.gov/pubmed/18495017
http://dx.doi.org/10.1186/1751-0473-3-8

Ejemplares similares