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Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules

OBJECTIVE: Here we report the improved results of a new siRNA design program and analysis tool called siRNA_profile that reveals an additional criterion for bioinformatic search of highly functional siRNA sequences. METHODS: We retrospectively analysed over 2400 siRNA sequences from 34 genes and wit...

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Detalles Bibliográficos
Autores principales:	Muhonen, Pirkko, Parthasarathy, Ranga N, Janckila, Anthony J, Büki, Kalman G, Väänänen, H Kalervo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424050/ https://www.ncbi.nlm.nih.gov/pubmed/18495017 http://dx.doi.org/10.1186/1751-0473-3-8

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