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Association of ABCB1 genetic variants with renal function in Africans and in Caucasians

BACKGROUND: The P-glycoprotein, encoded by the ABCB1 gene, is expressed in human endothelial and mesangial cells, which contribute to control renal plasma flow and glomerular filtration rate. We investigated the association of ABCB1 variants with renal function in African and Caucasian subjects. MET...

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Detalles Bibliográficos
Autores principales: Bochud, Murielle, Eap, Chin B, Maillard, Marc, Johnson, Toby, Vollenweider, Peter, Bovet, Pascal, Elston, Robert C, Bergmann, Sven, Beckmann, Jacques S, Waterworth, Dawn M, Mooser, Vincent, Gabriel, Anne, Burnier, Michel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424071/
https://www.ncbi.nlm.nih.gov/pubmed/18518969
http://dx.doi.org/10.1186/1755-8794-1-21