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Model-Based Hypothesis Testing of Key Mechanisms in Initial Phase of Insulin Signaling
Type 2 diabetes is characterized by insulin resistance of target organs, which is due to impaired insulin signal transduction. The skeleton of signaling mediators that provide for normal insulin action has been established. However, the detailed kinetics, and their mechanistic generation, remain inc...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424138/ https://www.ncbi.nlm.nih.gov/pubmed/18551197 http://dx.doi.org/10.1371/journal.pcbi.1000096 |