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A Unique Carrier for Delivery of Therapeutic Compounds beyond the Blood-Brain Barrier

BACKGROUND: Therapeutic intervention in many neurological diseases is thwarted by the physical obstacle formed by the blood-brain barrier (BBB) that excludes most drugs from entering the brain from the blood. Thus, identifying efficacious modes of drug delivery to the brain remains a “holy grail” in...

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Detalles Bibliográficos
Autores principales: Karkan, Delara, Pfeifer, Cheryl, Vitalis, Timothy Z., Arthur, Gavin, Ujiie, Maki, Chen, Qingqi, Tsai, Sam, Koliatis, Gerrasimo, Gabathuler, Reinhard, Jefferies, Wilfred A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424243/
https://www.ncbi.nlm.nih.gov/pubmed/18575595
http://dx.doi.org/10.1371/journal.pone.0002469