Prdm1- and Sox6-mediated transcriptional repression specifies muscle fibre type in the zebrafish embryo

The zebrafish u-boot (ubo) gene encodes the transcription factor Prdm1, which is essential for the specification of the primary slow-twitch muscle fibres that derive from adaxial cells. Here, we show that Prdm1 functions by acting as a transcriptional repressor and that slow-twitch-specific muscle g...

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Detalles Bibliográficos
Autores principales: von Hofsten, Jonas, Elworthy, Stone, Gilchrist, Michael J, Smith, James C, Wardle, Fiona C, Ingham, Philip W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Scientific Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424280/
https://www.ncbi.nlm.nih.gov/pubmed/18535625
http://dx.doi.org/10.1038/embor.2008.73

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424280/
https://www.ncbi.nlm.nih.gov/pubmed/18535625
http://dx.doi.org/10.1038/embor.2008.73

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