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Network-based global inference of human disease genes

Deciphering the genetic basis of human diseases is an important goal of biomedical research. On the basis of the assumption that phenotypically similar diseases are caused by functionally related genes, we propose a computational framework that integrates human protein–protein interactions, disease...

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Detalles Bibliográficos
Autores principales: Wu, Xuebing, Jiang, Rui, Zhang, Michael Q, Li, Shao
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424293/
https://www.ncbi.nlm.nih.gov/pubmed/18463613
http://dx.doi.org/10.1038/msb.2008.27