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Recurrent design patterns in the feedback regulation of the mammalian signalling network

Biochemical networks are characterized by recurrent patterns and motifs, but the design principles underlying the dynamics of the mammalian intracellular signalling network remain unclear. We systematically analysed decay rates of 134 signalling proteins and investigated their gene expression profil...

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Detalles Bibliográficos
Autores principales: Legewie, Stefan, Herzel, Hanspeter, Westerhoff, Hans V, Blüthgen, Nils
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424294/
https://www.ncbi.nlm.nih.gov/pubmed/18463614
http://dx.doi.org/10.1038/msb.2008.29