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Recurrent design patterns in the feedback regulation of the mammalian signalling network
Biochemical networks are characterized by recurrent patterns and motifs, but the design principles underlying the dynamics of the mammalian intracellular signalling network remain unclear. We systematically analysed decay rates of 134 signalling proteins and investigated their gene expression profil...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424294/ https://www.ncbi.nlm.nih.gov/pubmed/18463614 http://dx.doi.org/10.1038/msb.2008.29 |