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Understanding NF-κB signaling via mathematical modeling

Mammalian inflammatory signaling, for which NF-κB is a principal transcription factor, is an exquisite example of how cellular signaling pathways can be regulated to produce different yet specific responses to different inflammatory insults. Mathematical models, tightly linked to experiment, have be...

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Detalles Bibliográficos
Autores principales: Cheong, Raymond, Hoffmann, Alexander, Levchenko, Andre
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424295/
https://www.ncbi.nlm.nih.gov/pubmed/18463616
http://dx.doi.org/10.1038/msb.2008.30