Chemical mapping of cytosines enzymatically flipped out of the DNA helix

Haloacetaldehydes can be employed for probing unpaired DNA structures involving cytosine and adenine residues. Using an enzyme that was structurally proven to flip its target cytosine out of the DNA helix, the HhaI DNA methyltransferase (M.HhaI), we demonstrate the suitability of the chloroacetaldeh...

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Detalles Bibliográficos
Autores principales: Daujotytė, Dalia, Liutkevičiūtė, Zita, Tamulaitis, Gintautas, Klimašauskas, Saulius
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425465/
https://www.ncbi.nlm.nih.gov/pubmed/18450817
http://dx.doi.org/10.1093/nar/gkn200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425465/
https://www.ncbi.nlm.nih.gov/pubmed/18450817
http://dx.doi.org/10.1093/nar/gkn200

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