Chemical mapping of cytosines enzymatically flipped out of the DNA helix

Haloacetaldehydes can be employed for probing unpaired DNA structures involving cytosine and adenine residues. Using an enzyme that was structurally proven to flip its target cytosine out of the DNA helix, the HhaI DNA methyltransferase (M.HhaI), we demonstrate the suitability of the chloroacetaldeh...

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Dettagli Bibliografici
Autori principali: Daujotytė, Dalia, Liutkevičiūtė, Zita, Tamulaitis, Gintautas, Klimašauskas, Saulius
Natura: testo
Lingua:English
Pubblicazione: Oxford University Press 2008
Soggetti:
Methods Online
Accesso online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425465/
https://www.ncbi.nlm.nih.gov/pubmed/18450817
http://dx.doi.org/10.1093/nar/gkn200

Accesso online

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425465/
https://www.ncbi.nlm.nih.gov/pubmed/18450817
http://dx.doi.org/10.1093/nar/gkn200

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