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Identification of transcriptional regulatory cascades in retinoic acid-induced growth arrest of HepG2 cells

All-trans retinoic acid (ATRA) is a potent inducer of cell differentiation and growth arrest. Here, we investigated ATRA-induced regulatory cascades associated with growth arrest of the human hepatoma cell line HepG2. ATRA induced >2-fold changes in the expression of 402 genes including 55 linked...

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Detalles Bibliográficos
Autores principales: Nakanishi, Misato, Tomaru, Yasuhiro, Miura, Hisashi, Hayashizaki, Yoshihide, Suzuki, Masanori
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425469/
https://www.ncbi.nlm.nih.gov/pubmed/18445634
http://dx.doi.org/10.1093/nar/gkn066