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Enzymatic synthesis of structure-free DNA with pseudo-complementary properties

Long single-stranded DNAs and RNAs possess considerable secondary structure under conditions that support stable hybrid formation with oligonucleotides. Consequently, different oligomeric probes can hybridize to the same target with efficiencies that vary by several orders of magnitude. The ability...

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Detalles Bibliográficos
Autores principales: Lahoud, Georges, Timoshchuk, Victor, Lebedev, Alexandre, de Vega, Miguel, Salas, Margarita, Arar, Khalil, Hou, Ya-Ming, Gamper, Howard
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425472/
https://www.ncbi.nlm.nih.gov/pubmed/18448471
http://dx.doi.org/10.1093/nar/gkn209