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Enzymatic synthesis of structure-free DNA with pseudo-complementary properties
Long single-stranded DNAs and RNAs possess considerable secondary structure under conditions that support stable hybrid formation with oligonucleotides. Consequently, different oligomeric probes can hybridize to the same target with efficiencies that vary by several orders of magnitude. The ability...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425472/ https://www.ncbi.nlm.nih.gov/pubmed/18448471 http://dx.doi.org/10.1093/nar/gkn209 |