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Inhibitory effect of a short Z-DNA forming sequence on transcription elongation by T7 RNA polymerase

DNA sequences capable of forming unusual secondary structures can be a source of genomic instability. In some cases that instability might be affected by transcription, as recently shown for the Z-DNA forming sequence (CG)(14), which causes genomic instability both in mammalian cells and in bacteria...

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Detalles Bibliográficos
Autores principales: Ditlevson, Jennifer V., Tornaletti, Silvia, Belotserkovskii, Boris P., Teijeiro, Virginia, Wang, Guliang, Vasquez, Karen M., Hanawalt, Philip C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425487/
https://www.ncbi.nlm.nih.gov/pubmed/18400779
http://dx.doi.org/10.1093/nar/gkn136