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Inhibitory effect of a short Z-DNA forming sequence on transcription elongation by T7 RNA polymerase
DNA sequences capable of forming unusual secondary structures can be a source of genomic instability. In some cases that instability might be affected by transcription, as recently shown for the Z-DNA forming sequence (CG)(14), which causes genomic instability both in mammalian cells and in bacteria...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425487/ https://www.ncbi.nlm.nih.gov/pubmed/18400779 http://dx.doi.org/10.1093/nar/gkn136 |