A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells

The eukaryotic Ccr4/Caf1/Not complex is involved in deadenylation of mRNAs. The Caf1 and Ccr4 subunits both potentially have deadenylating enzyme activity. We investigate here the roles of Ccr4 and Caf1 in deadenylation in two organisms that separated early in eukaryotic evolution: humans and trypan...

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Detalles Bibliográficos
Autores principales: Schwede, Angela, Ellis, Louise, Luther, Julia, Carrington, Mark, Stoecklin, Georg, Clayton, Christine
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425496/
https://www.ncbi.nlm.nih.gov/pubmed/18442996
http://dx.doi.org/10.1093/nar/gkn108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2425496/
https://www.ncbi.nlm.nih.gov/pubmed/18442996
http://dx.doi.org/10.1093/nar/gkn108

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