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Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters
BACKGROUND: Human metapneumovirus (hMPV) infection can cause acute lower respiratory tract illness in infants, the immunocompromised, and the elderly. Currently there are no licensed preventative measures for hMPV infections. Using a variant of hMPV/NL/1/00 that does not require trypsin supplementat...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426676/ https://www.ncbi.nlm.nih.gov/pubmed/18519001 http://dx.doi.org/10.1186/1743-422X-5-69 |