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Deletion of human metapneumovirus M2-2 increases mutation frequency and attenuates growth in hamsters

BACKGROUND: Human metapneumovirus (hMPV) infection can cause acute lower respiratory tract illness in infants, the immunocompromised, and the elderly. Currently there are no licensed preventative measures for hMPV infections. Using a variant of hMPV/NL/1/00 that does not require trypsin supplementat...

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Detalles Bibliográficos
Autores principales:	Schickli, Jeanne H, Kaur, Jasmine, MacPhail, Mia, Guzzetta, Jeanne M, Spaete, Richard R, Tang, Roderick S
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426676/ https://www.ncbi.nlm.nih.gov/pubmed/18519001 http://dx.doi.org/10.1186/1743-422X-5-69

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