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Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease

BACKGROUND: It has recently become apparent that neuroinflammation may play a significant role in Parkinson's disease (PD). This is also the case in animal paradigms of the disease. The potential neuroprotective action of the glucagon-like peptide 1 receptor (GLP-1R) agonist exendin-4 (EX-4), w...

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Detalles Bibliográficos
Autores principales: Harkavyi, Alexander, Abuirmeileh, Amjad, Lever, Rebecca, Kingsbury, Ann E, Biggs, Christopher S, Whitton, Peter S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426681/
https://www.ncbi.nlm.nih.gov/pubmed/18492290
http://dx.doi.org/10.1186/1742-2094-5-19