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Sirolimus therapy following early cyclosporine withdrawal in transplant patients: mechanisms of action and clinical results

Cyclosporine (CsA), a member of the family of calcineurin inhibitors, is a cornerstone of the immunosuppressive treatments used after organ transplantation. However, it exhibits significant toxicity, including nephrotoxicity and increased cardiovascular risk factors. CsA withdrawal has been used as...

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Detalles Bibliográficos
Autor principal: Thervet, Eric
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426801/
https://www.ncbi.nlm.nih.gov/pubmed/17717968