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Sirolimus therapy following early cyclosporine withdrawal in transplant patients: mechanisms of action and clinical results
Cyclosporine (CsA), a member of the family of calcineurin inhibitors, is a cornerstone of the immunosuppressive treatments used after organ transplantation. However, it exhibits significant toxicity, including nephrotoxicity and increased cardiovascular risk factors. CsA withdrawal has been used as...
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Formato: | Texto |
Lenguaje: | English |
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Dove Medical Press
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426801/ https://www.ncbi.nlm.nih.gov/pubmed/17717968 |