Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers

OBJECTIVES: The WHO recommends artemisinin-based combination therapies for treatment of uncomplicated falciparum malaria. At least 15 African countries have adopted artesunate plus amodiaquine as treatment policy. As no pharmacokinetic data on this combination have been published to date, we investi...

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Detalles Bibliográficos
Autores principales: Orrell, Catherine, Little, Francesca, Smith, Peter, Folb, Peter, Taylor, Walter, Olliaro, Piero, Barnes, Karen I.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Pharmacokinetics and Disposition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426925/
https://www.ncbi.nlm.nih.gov/pubmed/18415093
http://dx.doi.org/10.1007/s00228-007-0452-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426925/
https://www.ncbi.nlm.nih.gov/pubmed/18415093
http://dx.doi.org/10.1007/s00228-007-0452-8

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