Cargando…
Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers
OBJECTIVES: The WHO recommends artemisinin-based combination therapies for treatment of uncomplicated falciparum malaria. At least 15 African countries have adopted artesunate plus amodiaquine as treatment policy. As no pharmacokinetic data on this combination have been published to date, we investi...
Autores principales: | Orrell, Catherine, Little, Francesca, Smith, Peter, Folb, Peter, Taylor, Walter, Olliaro, Piero, Barnes, Karen I. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426925/ https://www.ncbi.nlm.nih.gov/pubmed/18415093 http://dx.doi.org/10.1007/s00228-007-0452-8 |
Ejemplares similares
-
Tolerability and pharmacokinetics of non-fixed and fixed combinations of artesunate and amodiaquine in Malaysian healthy normal volunteers
por: Navaratnam, Visweswaran, et al.
Publicado: (2009) -
The effect of dipyridamole on the pharmacokinetics of metformin: a randomized crossover study in healthy volunteers
por: El Messaoudi, S., et al.
Publicado: (2016) -
Predictive performance of parent-metabolite population pharmacokinetic models of (S)-ketamine in healthy volunteers
por: Otto, M. E., et al.
Publicado: (2021) -
Population pharmacokinetics of phenytoin after intravenous administration of fosphenytoin sodium in pediatric patients, adult patients, and healthy volunteers
por: Tanaka, Jun, et al.
Publicado: (2012) -
The pharmacokinetic interaction between nasally administered naloxone and the opioid remifentanil in human volunteers
por: Tylleskar, Ida, et al.
Publicado: (2021)