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p190RhoGAP is the convergence point of adhesion signals from α(5)β(1) integrin and syndecan-4

The fibronectin receptors α(5)β(1) integrin and syndecan-4 cocluster in focal adhesions and coordinate cell migration by making individual contributions to the suppression of RhoA activity during matrix engagement. p190Rho–guanosine triphosphatase–activating protein (GAP) is known to inhibit RhoA du...

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Detalles Bibliográficos
Autores principales: Bass, Mark D., Morgan, Mark R., Roach, Kirsty A., Settleman, Jeffrey, Goryachev, Andrew B., Humphries, Martin J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426943/
https://www.ncbi.nlm.nih.gov/pubmed/18541700
http://dx.doi.org/10.1083/jcb.200711129