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p190RhoGAP is the convergence point of adhesion signals from α(5)β(1) integrin and syndecan-4
The fibronectin receptors α(5)β(1) integrin and syndecan-4 cocluster in focal adhesions and coordinate cell migration by making individual contributions to the suppression of RhoA activity during matrix engagement. p190Rho–guanosine triphosphatase–activating protein (GAP) is known to inhibit RhoA du...
Autores principales: | Bass, Mark D., Morgan, Mark R., Roach, Kirsty A., Settleman, Jeffrey, Goryachev, Andrew B., Humphries, Martin J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426943/ https://www.ncbi.nlm.nih.gov/pubmed/18541700 http://dx.doi.org/10.1083/jcb.200711129 |
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