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A neuron-specific cytoplasmic dynein isoform preferentially transports TrkB signaling endosomes

Cytoplasmic dynein is the multisubunit motor protein for retrograde movement of diverse cargoes to microtubule minus ends. Here, we investigate the function of dynein variants, defined by different intermediate chain (IC) isoforms, by expressing fluorescent ICs in neuronal cells. Green fluorescent p...

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Detalles Bibliográficos
Autores principales: Ha, Junghoon, Lo, Kevin W.-H., Myers, Kenneth R., Carr, Tiffany M., Humsi, Michael K., Rasoul, Bareza A., Segal, Rosalind A., Pfister, K. Kevin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426944/
https://www.ncbi.nlm.nih.gov/pubmed/18559670
http://dx.doi.org/10.1083/jcb.200803150