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Multiple functions of the von Willebrand Factor A domain in matrilins: secretion, assembly, and proteolysis

The von Willebrand Factor A (vWF A) domain is one of the most widely distributed structural modules in cell-matrix adhesive molecules such as intergrins and extracellular matrix proteins. Mutations in the vWF A domain of matrilin-3 cause multiple epiphyseal dysplasia (MED), however the pathological...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Wang, Zheng-ke, Luo, Jun-ming, Kanbe, Katsuaki, Chen, Qian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427018/
https://www.ncbi.nlm.nih.gov/pubmed/18518980
http://dx.doi.org/10.1186/1749-799X-3-21