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Analysis of the effects of exposure to acute hypoxia on oxidative lesions and tumour progression in a transgenic mouse breast cancer model

BACKGROUND: Tumour hypoxia is known to be a poor prognostic indicator, predictive of increased risk of metastatic disease and reduced survival. Genomic instability has been proposed as one of the potential mechanisms for hypoxic tumour progression. Both of these features are commonly found in many c...

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Detalles Bibliográficos
Autores principales: Kalliomäki, Tuula M, McCallum, Gordon, Lunt, Sarah Jane, Wells, Peter G, Hill, Richard P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427038/
https://www.ncbi.nlm.nih.gov/pubmed/18507854
http://dx.doi.org/10.1186/1471-2407-8-151