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Analysis of the effects of exposure to acute hypoxia on oxidative lesions and tumour progression in a transgenic mouse breast cancer model
BACKGROUND: Tumour hypoxia is known to be a poor prognostic indicator, predictive of increased risk of metastatic disease and reduced survival. Genomic instability has been proposed as one of the potential mechanisms for hypoxic tumour progression. Both of these features are commonly found in many c...
Autores principales: | Kalliomäki, Tuula M, McCallum, Gordon, Lunt, Sarah Jane, Wells, Peter G, Hill, Richard P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427038/ https://www.ncbi.nlm.nih.gov/pubmed/18507854 http://dx.doi.org/10.1186/1471-2407-8-151 |
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