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Characterization of immortalized MARCO and SR-AI/II-deficient murine alveolar macrophage cell lines

BACKGROUND: Alveolar macrophages (AM) avidly bind and ingest unopsonized inhaled particles and bacteria through class A scavenger receptors (SRAs) MARCO and SR-AI/II. Studies to characterize the function of these SRAs have used AMs from MARCO or SR-AI/II null mice, but this approach is limited by th...

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Detalles Bibliográficos
Autores principales: Zhou, Hongwei, Imrich, Amy, Kobzik, Lester
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427050/
https://www.ncbi.nlm.nih.gov/pubmed/18452625
http://dx.doi.org/10.1186/1743-8977-5-7