Cargando…

Capturing Pluripotency

In this Essay, we argue that pluripotent epiblast founder cells in the embryo and embryonic stem (ES) cells in culture represent the ground state for a mammalian cell, signified by freedom from developmental specification or epigenetic restriction and capacity for autonomous self-replication. We spe...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva, Jose, Smith, Austin
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427053/
https://www.ncbi.nlm.nih.gov/pubmed/18295569
http://dx.doi.org/10.1016/j.cell.2008.02.006